Dr. Kohei Kido is Graduate Student in Faculty of Sport and Health Science of Ritsumeikan University, and his research manuscript was accepted and published in Physiological Reports, which collaborated with Professor Isaka Tadao and Satoshi Fujita in Faculty of Sport and Health Science of Ritsumeikan University, Professor Takafumi Hamaoka in Tokyo Medical University, and Postdoctoral Fellow Tadashi Suga in Ritsumeikan Global Innovation Research Organization. The study revealed that ischemic preconditioning (IPC) to exercising muscle can enhance exercise endurance during whole-body cycling exercise test. Moreover, the study showed that the IPC-induced effect may result from mitochondrial activation in local skeletal muscle.