Recent Publications

Expression, purification, and enzymatic characterization of human UDP-glucose:glycoprotein glucosyltransferase-Selenoprotein F complex from Sf9 insect cells.
H Tomii, T Kikuma, H Kajiura, K Sano, H Matsumura, Y Ito, Y Kajihara, Y Takeda.
Protein Expression and Purification (2025) 231, 106719.

Bi-allelic UGGT1 variants cause a congenital disorder of glycosylation.
Z Dardas, L Harrold, DG Calame, CG Salter, T Kikuma, KP Guay, BG Ng, K Sano, AK Saad, H Du, R Sangermano, SG Patankar, SN Jhangiani, S Gürsoy, MS Abdel-Hamid, MKH Ahmed, R Maroofian, R Kaiyrzhanov, K Salayev, WD Jones, A Pérez Caballero, L McGavin, M Spiller, M Durkie, N Wood, L O’Grady, P Goldenberg, AM Neumeyer, A Begtrup, SF Abdel-Ghafar, MS Zaki, H Van Esch, JE Posey, OK Wenger, EM Scott, KM Bujakowska, RA Gibbs, D Pehlivan, D Marafi, JS Leslie, N Ubeyratna, J Day, M Owens, J Settle, S Balkhy, A Tamim, L Alabdi, FS Alkuraya, Y Takeda, HH Freeze, DN Hebert, JR Lupski, AH Crosby, EL Baple.
The American Journal of Human Genetics (2025).

Development of a Calreticulin-targeting Glycan Ligand Based on a Hybrid Binding Concept.
T Kuribara, T Kojima, Y Kobayashi, M Hirose, K Shibayama, Y Takeda, K Totani.
Glycobiology (2025) cwaf015.

Biochemical characterization of l-asparagine synthetase from Streptococcus thermophilus and its application in the enzymatic synthesis of β-aspartyl compounds.
D Matsui, T Yamada, J Hayashi, Y Toyotake, Y Takeda, M Wakayama.
Journal of bioscience and bioengineering (2024) 138(3), 206–211.

Preparation and degradability of novel cross-linked functional hydrogels from enzymatic synthesized α-1, 3-glucan and its carboxymethyl derivative.
Z Su, H Kinoshita, M Ogaito, Y Takeda, Y Toyotake, M Wakayama.
Chemistry Letters (2024) 53(7), upae120.

Synthesis of Sucrose-Mimicking Disaccharide by Intramolecular Aglycone Delivery.
K Sano, A Ishiwata, H Takamori, T Kikuma, K Tanaka, Y Ito, Y Takeda.
Molecules (2024) 29(8), 1771.

Synthesis of azide-modified glycerophospholipid precursor analogs for detection of enzymatic reactions.
R Ueshima, T Kikuma, K Sano, N Toda, P Greimel, Y Takeda.
ChemBioChem (2024) 25(3), e202300699.

Efficient synthesis of cytidine diphosphate diacylglycerol: A crucial precursor of glycerophospholipids biosynthesis.
Y Kitaura, R Ueshima, K Sano, T Kikuma, Y Takeda.
Tetrahedron Letters (2023) 131, 154781.

Synthesis and characterization of novel self-assembled amphiphilic α-1, 3-glucan nanomicelles for drug delivery.
Z Su, Y Takeda, D Matsui, Y Toyotake, M Wakayama.
Colloid and Polymer Science (2023) 301, 1337–1350.

Convergent synthesis of oligomannose-type glycans via step-economical construction of branch structures.
K Sano, N Ishii, S Takahashi, Y Takeda, I Matsuo.
Carbohydrate Research (2023) 525, 108764.

Squaryl group-modified UDP analogs as inhibitors of the ER resident folding sensor enzyme UGGT.
J Abe, Y Takeda, T Kikuma, Y Kizuka, H Kajiura, Y Kajihara, Y Ito.
Chemical Communications (2023) 59, 2803–2806.

AeiA is a novel autophagy-related protein that promotes peroxisome degradation by pexophagy in Aspergillus oryzae.
J Nishio, Y Takahashi, M Kasahara, Y Takeda, T Kikuma.
FEBS Letters (2023) 597(5), 608–617.