Biomolecular
Chemistry
Laboratory

About Us

研究室について

Research

研究テーマ

Publications

最近の発表論文

• 2025

  Expression, purification, and enzymatic characterization of human UDP-glucose:glycoprotein glucosyltransferase-Selenoprotein F complex from Sf9 insect cells.

  H Tomii, T Kikuma, H Kajiura, K Sano, H Matsumura, Y Ito, Y Kajihara, Y Takeda.

  Protein Expression and Purification (2025) 231, 106719.

• 2025

  Bi-allelic UGGT1 variants cause a congenital disorder of glycosylation.

  Z Dardas, L Harrold, DG Calame, … Y Takeda, HH Freeze, DN Hebert, JR Lupski, AH Crosby, EL Baple.

  The American Journal of Human Genetics (2025).

• 2025

  Development of a Calreticulin-targeting Glycan Ligand Based on a Hybrid Binding Concept.

  T Kuribara, T Kojima, Y Kobayashi, M Hirose, K Shibayama, Y Takeda, K Totani.

  Glycobiology (2025) cwaf015.

• 2024

  Biochemical characterization of l-asparagine synthetase from Streptococcus thermophilus and its application in the enzymatic synthesis of β-aspartyl compounds.

  D Matsui, T Yamada, J Hayashi, Y Toyotake, Y Takeda, M Wakayama.

  Journal of Bioscience and Bioengineering (2024) 138(3), 206–211.

• 2024

  Preparation and degradability of novel cross-linked functional hydrogels from enzymatic synthesized α-1,3-glucan and its carboxymethyl derivative.

  Z Su, H Kinoshita, M Ogaito, Y Takeda, Y Toyotake, M Wakayama.

  Chemistry Letters (2024) 53(7), upae120.

• 2024

  Synthesis of Sucrose-Mimicking Disaccharide by Intramolecular Aglycone Delivery.

  K Sano, A Ishiwata, H Takamori, T Kikuma, K Tanaka, Y Ito, Y Takeda.

  Molecules (2024) 29(8), 1771.

• 2024

  Synthesis of azide-modified glycerophospholipid precursor analogs for detection of enzymatic reactions.

  R Ueshima, T Kikuma, K Sano, N Toda, P Greimel, Y Takeda.

  ChemBioChem (2024) 25(3), e202300699.

• 2023

  Efficient synthesis of cytidine diphosphate diacylglycerol: A crucial precursor of glycerophospholipids biosynthesis.

  Y Kitaura, R Ueshima, K Sano, T Kikuma, Y Takeda.

  Tetrahedron Letters (2023) 131, 154781.

• 2023

  Synthesis and characterization of novel self-assembled amphiphilic α-1,3-glucan nanomicelles for drug delivery.

  Z Su, Y Takeda, D Matsui, Y Toyotake, M Wakayama.

  Colloid and Polymer Science (2023) 301, 1337–1350.

• 2023

  Convergent synthesis of oligomannose-type glycans via step-economical construction of branch structures.

  K Sano, N Ishii, S Takahashi, Y Takeda, I Matsuo.

  Carbohydrate Research (2023) 525, 108764.

• 2023

  Squaryl group-modified UDP analogs as inhibitors of the ER resident folding sensor enzyme UGGT.

  J Abe, Y Takeda, T Kikuma, Y Kizuka, H Kajiura, Y Kajihara, Y Ito.

  Chemical Communications (2023) 59, 2803–2806.

• 2023

  AeiA is a novel autophagy-related protein that promotes peroxisome degradation by pexophagy in Aspergillus oryzae.

  J Nishio, Y Takahashi, M Kasahara, Y Takeda, T Kikuma.

  FEBS Letters (2023) 597(5), 608–617.

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