Research Topic
Exploring methods for the pathological analysis, prevention, and treatment of various gastrointestinal diseases
The gastrointestinal tract is divided into the upper gastrointestinal tract composed of the esophagus, stomach, and duodenum, and the lower gastrointestinal tract composed of the small and large intestines. The pathogenetic factors for diseases in each tract are wide and varied. Although progress has been made in elucidating many of these pathologies, there is a noticeable impact of the aging of society and changes in environment and dietary habits on the gastrointestinal tract. In addition to the expected effects of widely-used treatments for various diseases, damage to the gastrointestinal mucosa is one side-effect that is regarded as problematic. In this laboratory, we are conducting research aimed at proposing safe and appropriate drug therapies by using pharmacological, biochemical, and molecular biological techniques to establish animal models for understanding pathologies and explore the factors involved therein, all in an effort to elucidate the pathogenesis of gastrointestinal injuries (from the esophagus to the large intestine) caused by various clinical drugs (e.g., anti-inflammatory drugs, anti-thrombotic drugs, and anti-cancer drugs). Furthermore, to shed light on the heretofore unknown pathologies of refractory gastrointestinal disorders and functional dyspepsia, we are also exploring the possibility of drug repositioning—that is, identifying new pharmacological effects of approved drugs whose safety and in vivo disposition have been sufficiently demonstrated for humans—to treat gastrointestinal diseases.
Staff
Professor
Kikuko AMAGASE (PhD)
Research Fellow
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Students
Graduate student | Undergraduate student | |
PhD Course 4th year(Pharmacy) | 6th year (Pharmacy) | |
Shizuka JONAN | Yuu ADACHI | |
Takumi ITAKA | ||
PhD Course 1st year(Pharmacy) | Anna TANAKA | |
Yuuki OTSUKA | Ayano HOSHINA | |
Master Course 2nd year(Pharmaceutical Science) | 5th year (Pharmacy) | |
Ryo SUGAHARA | Mika SAITO | |
Haruto FUKATSU | Yuuto SUGISAWA | |
Ayana FUJIWARA | Saori FUKE | |
Satoshi YAGUCHI | ||
Master Course 1st year(Pharmaceutical Science) | ||
Issei IKEDA | 4th year (Pharmacy) | |
Taisei TSUJII | Yui KUWAHARA | |
Mai HANEDA | Karin SHIMA | |
Chihiro SHIN | ||
Kirika NISHINAKA | ||
Yujiro FUJINO | ||
Konoka MATSUBARA | ||
4th year (Pharmaceuctial Science) | ||
Chisato OOKI | ||
Syouma KITANISHI | ||
Taito SHINCHI | ||
Kanako NISHIIRI | ||
Mizuki FUKUHARA | ||
3rd year (Pharmacy) | ||
Shota OYAMA | ||
Chihiro KUBOTA | ||
Ayaka SAKAMOTO | ||
Waka SHINOHARA | ||
Sumika HORII | ||
3rd year (Pharmaceuctial Science) | ||
Haruka KAWASHIRI | ||
Yui KITAZAWA | ||
Honoka MASUDA | ||
Tomoha MORIKUBO | ||
Graduates
March, 2023 | March, 2022 | March, 2021 | March, 2020 | |||
[Master of Pharmaceutical Science] | [Master of Pharmaceutical Science] | [Bachelor] | [Bachelor] | |||
Hikaru OTSUKI | Daisuke KATO | Hikaru OTSUKI | Daisuke KATO | |||
Reiichiro SASAKI | Yuuya MASUDA | Reiichiro SASAKI | Yuuya MASUDA | |||
[Bachelor] | [Bachelor] | |||||
Naoka UNO | Kouya KIKUYAMA | |||||
Yuuki OTSUKA | Hina KIJIMA | |||||
Miyoko TAKAHASHI | Mayu NOMURA | |||||
Rikako NAKAI | Hikaru OTA | |||||
Miyu YAMAMOTO | Ryo SUGAHARA | |||||
Issei IKEDA | Haruto FUKATSU | |||||
Taisei TSUJII | Ayana FUJIWARA | |||||
Mai HANEDA |
Lab Enrollments
Nahla Hamouda, MD. PhD. | Egypt | 2019.4〜2021.3 (Research fellow) |
Nikoo Hasemi | Canada | 2022.9.19〜2022.10.21 |
Tahani Dakkak | Canada | 2022.10.24〜2022.11.25 |
Denise Choy | Canada | 2022.11.28~ 2023.1.13 |
Mikhail Krivykh | Canada | 2023.1.16~ 2023.2.10 |