研究業績

英語論文

  • Nakayama M, Hori A, Toyoura S, and Yamaguchi SI.
    Shaping of T Cell functions by Trogocytosis
    Cells 10, 1155, 2021
    https://doi.org/10.3390/cells10051155
  • Omori S, Tsugita M, Hoshikawa Y, Morita M, Ito F, Yamaguchi, S-I, Xie Q, Noyori O, Yamaguchi T, Takada A, Saitoh T, Toyokuni S, Akiba H, Nagata S, Kinoshita K, and Nakayama M.
    Tim4 recognizes carbon nanotubes and mediates phagocytosis leading to granuloma formation.
    Cell Rep. 34, 108734, 2021
    https://doi.org/10.1016/j.celrep.2021.108734
  • Kawashima M, Carreras J, Higuchi H, Kotaki R, Hoshina T, Okuyama K, Suzuki N, Kakizaki M, Miyatake Y, Ando K, Nakayama M, Umezu S, Horie R, Higuchi Y, Katagiri K, Goyama S, Kitamura T, Chamoto K, Yano S, Nakamura N, and Kotani A.
    PD-L1/L2 protein levels rapidly increase on monocytes via trogocytosis from tumor cells in classical Hodgkin lymphoma.
    Leukemia 34, 2405-2417, 2020. 
    https://doi.org/10.1038/s41375-020-0737-9
  • Nakayama M.
    Macrophage recognition of crystals and nanoparticles.
    Front. Immunol. 9, 103, 2018
    https://doi.org/10.3389/fimmu.2018.00103
  • Morimoto N, Takei R, Wakamura M, Oishi Y, Nakayama M, Suzuki M, Yamamoto M, and Winnik FM.
    Fast and effective mitochondrial delivery of omega-Rhodamine-B-polysulfobetaine-PEG copolymers.
    Sci. Rep. 8, 1128, 2018
    https://doi.org/10.1038/s41598-018-19598-2
  • Tsugita M, Morimoto N, Tashiro M, Kinoshita K, and Nakayama M.
    SR-B1 is a silica receptor that mediates canonical inflammasome activation.
    Cell Rep. 18, 1298-1311, 2017
    This article was selected by the Faculty of 1000 as an article of special significance in biology and medicine.
    https://doi.org/10.1016/j.celrep.2017.01.004
  • Takeda K, Nakayama M, Hayakawa Y, Kojima Y, Ikeda H, Imai N, Ogasawara K, Okumura K, Thomas DM, and Smyth MJ.
    IFN-g is required for cytotoxic T cell-dependent cancer genome immunoediting.
    Nature Commun. 8:14607, 2017
    https://doi.org/10.1038/ncomms14607
  • Tsugita M, Morimoto N, and Nakayama M.
    SiO2 and TiO2 nanoparticles synergistically trigger macrophage inflammatory responses.
    Part. Fibre. Toxicol. 14:11, 2017
    https://doi.org/10.1186/s12989-017-0192-6
  • Isshiki T, Akiba H, Nakayama M, Harada N, Okumura K, Homma, S, and Miyake S.
    Cutting Edge: Anti-TIM-3 treatment exacerbate pulmonary inflammation and fibrosis in mice.
    J. Immunol. 199, 3733-3737, 2017
    This article was selected by the Faculty of 1000 as an article of special significance in immunology.
    https://doi.org/10.4049/jimmunol.1700059
  • Funamoto K, Yoshino D, Matubara K, Zervantonakis IK, Funamoto K, Nakayama M, Masamune J, Kimura Y, and Kamm RD.
    Endothelial monolayer permeability under controlled oxygen tension.
    Integr. Biol (Camb). 19, 529-538, 2017
    https://doi.org/10.1039/c7ib00068e
  • Morimoto N, Wakamura M, Muramatsu K, Toita S, Nakayama M, Shoji W, Suzuki M, and Winnik FM.
    Membrane translocation and organelle-selective delivery steered by polymeric zwitterionic nanospheres.
    Biomacromolecules. 17, 1523-1535, 2016
    https://doi.org/10.1021/acs.biomac.6b00172
  • Sonofuchi K, Hagiwara Y, Koizumi Y, Chiba A, Kawano M, Nakayama M, Ogasawara K, Yabe Y, and Itoi E.
    Quantitative in vivo biocompatibility of new ultralow-nickel cobalt-chromium-molybdenum alloys.
    J. Orthop. Res. 34, 1505-1513, 2016
    https://doi.org/10.1002/jor.23150
  • Nakayama M.
    Antigen presentation by MHC-dressed cells.
    Front. Immunol. 5, 672, 2015
    https://doi.org/10.3389/fimmu.2014.00672
  • Kusaka T, Nakayama M, Nakamura K, Ishimiya M, Furusawa E, and Ogasawara K.
    Effect of silica particle size on macrophage inflammatory responses.
    PLoS ONE. 9, e92634, 2014
    https://doi.org/10.1371/journal.pone.0092634
  • Kawano M, Nakayama M, Aoshima Y, Nakamura K, Ono M, Nishiya T, Nakamura S, Takeda Y, Dobashi A, Takahashi A, Endo M, Ito A, Ueda K, Sato N, Higuchi S, Kondo T, Hashimoto S, Watanabe M, Watanabe M, Takahashi T, Sasaki K, Nakamura M, Sasazuki T, Narushima T, Suzuki R, and Ogasawara K.
    NKG2D+ IFN-g+ CD8+ T cells are responsible for palladium allergy.
    PLoS ONE. 9, e86810, 2014
    https://doi.org/10.1371/journal.pone.0086810
  • Watanabe M, Kudo Y, Kawano M, Nakayama M, Nakamura K, Kameda M, Ebara M, Sato T, Nakamura M, Omine K, Kametani Y Suzuki R and Ogasawara K.
    NKG2D functions as an activating receptor on natural killer cells in the common marmoset (Callithrix jacchus).
    Int. Immunol. 11, 597-606, 2014
    https://doi.org/10.1093/intimm/dxu053
  • Nakamura K, Nakayama M, Kawano M, Amagai R, Ishii T, Harigae H, and Ogasawara K.
    Fratricide of naturel killer cells dressed with tumor-derived NKG2D ligand.
    Proc. Natl. Acad. Sci. U. S. A. 110, 9421-9426, 2013
    https://doi.org/10.1073/pnas.1300140110
  • Yeung MY, McGrath MM, Nakayama M, Shimizu T, Boenisch O, Magee CN, Abdoli R, Akiba H, Ueno T, Turka LA, and Najafian N.
    Interruption of dendritic cell-mediated TIM-4 signaling induces regulatory T cells and promotes skin allograft survival.
    J. Immunol. 191, 4447-4455, 2013
    https://doi.org/10.4049/jimmunol.1300992
  • Nakamura K, Nakayama M, Kawano M, Ishii T, Harigae H, and Ogasawara K.
    NK-cell fratricide: Dynamic crosstalk between NK and cancer cells.
    Oncoimmunology. 2, e26529, 2013
    https://doi.org/10.4161/onci.26529
  • Nakayama M, Kurokawa K, Nakamura K, Lee BL, Sekimizu K, Kubagawa H, Hiramatsu K, Yagita H, Okumura K, Takai T, Underhill DM, Aderem A, and Ogasawara K.
    Inhibitory receptor PIR-B is exploited by Staphylococcus aureus for virulence.
    J. Immunol. 189, 5903-5911, 2012
    This article was selected by the Faculty of 1000 as an article of special significance in immunology.
    https://doi.org/10.4049/jimmunol.1201940
  • Nakayama M, Takeda K, Kawano M, Takai T, Ishii N, and Ogasawara K.
    Natural Killer (NK)-dendritic cell interactions generate MHC Class II-dressed NK cells that regulate CD4+ T cells.
    Proc. Natl. Acad. Sci. USA. 108, 18360-18365, 2011
    This article was selected by the Faculty of 1000 as the top 2% of published articles in biology and medicine.
    https://doi.org/10.1073/pnas.1110584108
  • Kojima Y, Nakayama M, Nishina T, Nakano H, Koyanagi M, Takeda K, Okumura K, and Yagita H.
    Importin beta1 protein-mediated nuclear localization of death receptor 5 (DR5) limits DR5/tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced cell death of human tumor cells.
    J. Biol. Chem. 286, 43383-43393, 2011
    https://doi.org/10.1074/jbc.M111.309377
  • Takeda K, Nakayama M, Sakaki M, hayakawa Y, Imawari M, Ogasawara K, Okumura K, and Smyth MJ.
    IFN-gamma production by lung NK cells is critical for the natural resistance to pulmonary metastasis of B16 melanoma in mice.
    J. Leukoc. Biol. 90, 777-785, 2011
    https://doi.org/10.1189/jlb.0411208
  • Nakayama M, Akiba H, Takeda K, Kojima Y, Hashiguchi M, Azuma M, Yagita H, and Okumura K.
    Tim-3 mediates phagocytosis of apoptotic cells and the cross-presentation.
    Blood 113, 3821-3830, 2009
    https://doi.org/10.1182/blood-2008-10-185884
  • Ebihara N, Nakayama M, Tokura T, Ushio H, and Murakami A.
    Expression and function of fibroblast growth factor-inducible 14 human corneal myofibroblasts.
    Exp. Eye Res. 89, 256-262, 2009
    https://doi.org/10.1016/j.exer.2009.03.014
  • Ebihara N, Nakayama M, Tokura T, Iwatsu M, Ushio H, and Murakami A.
    Proinflammatory effect of TWEAK/Fn14 interaction in human retinal pigment epithelial cells.
    Curr. Eye Res. 34, 836-844, 2009
    https://doi.org/10.3109/02713680903122037
  • Nakajima A, Kojima Y, Nakayama M, Yagita H, Okumura K, and Nakano H.
    Downregulation of c-FLIP promotes caspase-dependent JNK activation and reactive oxygen species accumulation in tumor cells.
    Oncogene 27, 76-84, 2008
    https://doi.org/10.1038/sj.onc.1210624
  • Nakayama M, Underhill DM, Petersen TW, Li B, Kitamura T, Takai T, and Aderem A.
    Paired immunoglobulin-like receptors bind to bacteria and shape TLR-mediated cytokine production.
    J. Immunol. 178, 4259-4350,2007
    https://doi.org/10.4049/jimmunol.178.7.4250
  • Kaduka Y, Takeda K, Nakayama M, Kinoshita K, Yagita H, and Okumura K.
    TWEAK mediates anti-tumor effect of tumor-infiltrating macrophage.
    Biochem. Biophys. Res. Commun. 331, 384-390, 2005
    https://doi.org/10.1016/j.bbrc.2005.03.176
  • Jin L, Nakao A, Nakayama M, Yamaguchi N, Kojima Y, Nakano N, Tsuboi R, Okumura K, Yagita H, and Ogawa H.
    Induction of RANTES by TWEAK/Fn14 interaction in human keratinocytes.
    J. Invest. Dermatol. 122,1175-1179, 2004
    https://doi.org/10.1111/j.0022-202X.2004.22419.x
  • Saitoh T, Nakayama M, Nakano H, Yagita H, Yamamoto N, and Yamaoka S.
    TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.
    J. Biol. Chem. 278, 36005-36012, 2003
    https://doi.org/10.1074/jbc.M304266200
  • Nakayama M, Ishidoh K, Kojima Y, Harada N, Kominami E, Okumura K, and Yagita H.
    Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death.
    J. Immunol. 170, 341-348, 2003
    https://doi.org/10.4049/jimmunol.170.1.341
  • Nakayama M, Harada N, Okumura K, and Yagita H.
    Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies.
    Biochem. Biophys. Res. Commun.306, 819-825, 2003
    https://doi.org/10.1016/s0006-291x(03)01051-9
  • Harada N, Nakayama M, Nakano H, Fukuchi Y, Yagita H, and Okumura K.
    Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells.
    Biochem. Biophys. Res. Commun. 306, 819-825, 2003
    https://doi.org/10.1016/s0006-291x(02)02670-0
  • Nakayama M, Ishidoh K, Kayagaki N, Kojima Y, Yamaguchi N, Nakano H, Kominami E, Okumura K, and Yagita H.
    Multiple pathways of TWEAK-induced cell death.
    J. Immunol. 168, 734-743, 2002
    https://doi.org/10.4049/jimmunol.168.2.734
  • Nakayama M, Kayagaki N, Yamaguchi N, Okumura K, and Yagita H.
    Involvement of TWEAK in interferon gamma-stimulated monocyte cytotoxicity.
    J. Exp. Med. 192, 1373-1380, 2000
    https://doi.org/10.1084/jem.192.9.1373
  • Nagao F, Nakayama M, Muto T, and Okumura K.
    Effects of a fermented milk drink containing Lactobacillus casei strain Shirota on the immune system in healthy human subjects.
    Biosci. Biotechnol. Biochem. 64, 2706-2708, 2000
    https://doi.org/10.1271/bbb.64.2706
  • Kayagaki N, Yamaguchi N, Nakayama M, Takeda K, Akiba H, Tsutsui H, Okamura H, NakanishiK, Okumura K, and Yagita H.
    Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.
    J. Immunol. 163, 1906-1913, 1999
  • Kayagaki N, Yamaguchi N, Nakayama M, Eto H, Okumura K, and Yagita H.
    Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs.
    J. Exp. Med. 189, 1451-1460, 1999
  • Kayagaki N, Yamaguchi N, Nakayama M, Kawasaki A, Akiba H, Okumura K, and Yagita H.
    Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity.
    J. Immunol. 162, 2639-2647, 1999
  • Degawa M, Nakayama M, Konno Y, Masubuchi K, and Yamazoe Y.
    2-Methoxy-4-nitroaniline and its isomers induce cytochrome P4501A (CYP1A) enzymes with different selectivities in the rat liver.
    Biochim. Biophys. Acta.1379, 391-398, 1998
  • Uehara N, Iwahori Y, Asamoto M, Baba-Toriyama H, Iigo M, Ochiai M, Nagao M, Nakayama M, Degawa M, Matsumoto K, Hirono I, Beppu H, Fujita K, and Tsuda H.
    Decreased levels of 2-amino-3-methylimidazo[4,5-f]quinoline-DNA adducts in rats treated with beta-carotene, alpha-tocopherol and freeze-dried aloe.
    Jpn. J. Cancer Res.(Cancer Sci.) 87, 342-348, 1996
  • Degawa M, Nakayama M, Yoshinari K, and Hashimoto Y.
    2-Methoxy-4-nitroaniline is a selective inducer of cytochrome P450IA2 (CYP1A2) in rat liver.
    Cancer Lett.96, 95-98, 1995

日本語総説、著書など

  • 中山勝文, 山口慎一朗
    CNTの毒性発現分子機構
    NEW DIAMOND 37巻26-29 2021年
  • 中山勝文
    第3章 抗原の捕捉とリンパ球への提示 翻訳
    基礎免疫学(原著Basic Immunology 6th Edition)中尾篤人 監訳
    エルゼビアジャパン 2020年
  • 中山勝文
    第11章 CD8陽性エフェクターT細胞の分化と機能 翻訳
    細胞分子免疫学(原著Cellular and Molecular Immunology 9th Edition)中尾篤人 監訳
    エルゼビアジャパン 2018年
  • 中山勝文
    新規シリカ受容体の同定
    臨床免疫・アレルギー科 科学評論社 68巻 p544-549, 2017年
  • 中山勝文
    Trogocytosisによる免疫調節機構
    臨床免疫・アレルギー科 科学評論社 67巻 p82-87, 2017年             
  • 中山勝文
    マクロファージによるナノ粒子の貪食
    バイオマテリアル-生体材料 日本バイオマテリアル学会 33巻, p134-139, 2015年
  • 中山勝文
    免疫の仕組み 第1〜6回
    科学の泉 2015年1月13日〜18日 河北新報社
  • 中山勝文, 小笠原康悦
    細菌感染におけるペア型受容体の役割
    Surgery Frontier メディカルレビュー社 21巻, p41-45, 2014年
  • 中山勝文
    Timファミリー分子を介したアポトーシス細胞貪食機構
    生物と化学 日本農芸化学会 会誌 48巻, p806-808, 2010年
  • 垣生園子, 中山勝文
    免疫学研究者のための道具箱 翻訳
    免疫生物学(原著Janeway’s Immunobiology 7th Edition)笹月健彦 監訳 南江堂 p735-p782, 2010年
  • 中山勝文
    TWEAK
    サイトカイン・増殖因子用語ライブラリー 菅村和夫 宮園浩平 宮澤恵二 田中伸幸 編 羊土社 p123-124, 2005 年
  • 中山勝文, 八木田秀雄, 奥村康
    細胞死誘導性TNFファミリー分子を介したキラー細胞の標的細胞破壊機構
    炎症・再生 日本炎症・再生医学会 会誌 23巻3, p144-150, 2003年
  • 中山勝文, 奥村康
    キラー細胞
    アレルギーリウマチ膠原病の最新治療医療 先端技術研究所 p16-20, 2003年
  • 中山勝文, 八木田秀雄, 奥村康
    TWEAK アポトーシスのすべて
    臨床免疫 科学論評社 38巻, p39-44, 2002年
  • 中山勝文
    TWEAK/Fn14レセプターシステム
    医学のあゆみ 医歯薬出版株式会社 203巻7号, 2002年
  • 中山勝文, 八木田秀雄, 奥村康
    TWEAKの標的細胞傷害
    免疫・Immunology Frontier メディカルレビュー社 4月号, p90-95, 2001年
  • 中山勝文, 榧垣伸彦, 八木田秀雄
    アポトーシスと免疫系 アポトーシスと疾患
    医薬ジャーナル社 6月号, p10-21, 2000年

研究業績(野依)

英語論文

  • Ogawa K, Kozuka Y, Uno H, Utsumi K, Noyori O, and Hosoki R

    Spontaneous and Immune Checkpoint Inhibitor-Induced Autoimmune Diseases: Analysis of Temporal Information by Using the Japanese Adverse Drug Event Report Database.

    Clin. Drug Investig. 41, 615-627, 2021
    https://doi.org/10.1007/s40261-021-01042-5

  • Nasser H, Adhikary P, Abdel-Daim A, Noyori O, Panaampon J, Kariya R, Okada S, Ma W, Baba M, Takizawa H, Yamane M, Niwa H, Suzu S.
    Establishment of bone marrow-derived M-CSF receptor-dependent self-renewing macrophages.
    Cell Death Discov. 6:63, 2020
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378060/
  • Lotfi S, Nasser H, Noyori O, Hiyoshi M, Takeuchi H, Koyanagi Y, Suzu S.
    M-Sec facilitates intercellular transmission of HIV-1 through multiple mechanisms.
    Retrovirology. 17(1):20, 2020
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350586/
  • Noyori O, Komohara Y, Nasser H, Hiyoshi M, Ma C, Pan C, Carreras J, Nakamura N, Sato A, Ando K, Okuno Y, Nosaka K, Matsuoka M, Suzu S.
    Expression of IL-34 correlates with macrophage infiltration and prognosis of diffuse large B-cell lymphoma.
    Clin Transl Immunology. 8(8):e1074, 2019
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691654/
  • Komohara Y, Noyori O, Saito Y, Takeya H, Baghdadi M, Kitagawa F, Hama N, Ishikawa K, Okuno Y, Nosaka K, Seino KI, Matsuoka M, Suzu S.
    Potential anti-lymphoma effect of M-CSFR inhibitor in adult T-cell leukemia/lymphoma.
    J Clin Exp Hematop. 58(4):152-160, 2018
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407477/
  • Siddiqui R, Suzu S, Ueno M, Nasser H, Koba R, Bhuyan F, Noyori O, Hamidi S, Sheng G, Yasuda-Inoue M, Hishiki T, Sukegawa S, Miyagi E, Strebel K, Matsushita S, Shimotohno K, Ariumi Y.
    Apolipoprotein E is an HIV-1-inducible inhibitor of viral production and infectivity in macrophages
    PLoS Pathog. 14(11):e1007372, 2018
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289579/
  • Furuyama W, Marzi A, Nanbo A, Haddock E, Maruyama J, Miyamoto H, Igarashi M, Yoshida R, Noyori O, Feldmann H, Takada A.
    Discovery of an antibody for pan-ebolavirus therapy.
    Sci Rep. 6:20514, 2016
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748290/
  • Hashimoto M, Bhuyan F, Hiyoshi M, Noyori O, Nasser H, Miyazaki M, Saito T, Kondoh Y, Osada H, Kimura S, Hase K, Ohno H, Suzu S.
    Potential Role of the Formation of Tunneling Nanotubes in HIV-1 Spread in Macrophages
    J Immunol. 196(4):1832-41, 2016
    https://www.jimmunol.org/content/196/4/1832.long
  • Kuroda M, Fujikura D, Nanbo A, Marzi A, Noyori O, Kajihara M, Maruyama J, Matsuno K, Miyamoto H, Yoshida R, Feldmann H, Takada A.
    Interaction between TIM-1 and NPC1 Is Important for Cellular Entry of Ebola Virus
    J Virol. 89(12):6481-93, 2015
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474285/
  • Kuroda M, Fujikura D, Noyori O, Kajihara M, Maruyama J, Miyamoto H, Yoshida R, Takada A.
    A polymorphism of the TIM-1 IgV domain: implications for the susceptibility to filovirus infection
    Biochem Biophys Res Commun. 455(3-4):223-8, 2014
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124303/
  • Noyori O, Nakayama E, Maruyama J, Yoshida R, Takada A.
    Suppression of Fas-mediated apoptosis via steric shielding by filovirus glycoproteins
    Biochem Biophys Res Commun. 441(4):994-8, 2013
    https://www.sciencedirect.com/science/article/pii/S0006291X13018913?via%3Dihub
  • Noyori O, Matsuno K, Kajihara M, Nakayama E, Igarashi M, Kuroda M, Isoda N, Yoshida R, Takada A.
    Differential potential for envelope glycoprotein-mediated steric shielding of host cell surface proteins among filoviruses
    Virology. 446(1-2):152-61, 2013
    https://www.sciencedirect.com/science/article/pii/S0042682213004492?via%3Dihub
  • Changula K, Yoshida R, Noyori O, Marzi A, Miyamoto H, Ishijima M, Yokoyama A, Kajihara M, Feldmann H, Mweene AS, Takada A.
    Mapping of conserved and species-specific antibody epitopes on the Ebola virus nucleoprotein
    Virus Res. 176(1-2):83-90, 2013
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787873/
  • Kajihara M, Matsuno K, Simulundu E, Muramatsu M, Noyori O, Manzoor R, Nakayama E, Igarashi M, Tomabechi D, Yoshida R, Okamatsu M, Sakoda Y, Ito K, Kida H, Takada A.
    An H5N1 highly pathogenic avian influenza virus that invaded Japan through waterfowl migration
    Jpn J Vet Res. 59(2-3):89-100, 2011
    https://pubmed.ncbi.nlm.nih.gov/21977732/
  • Matsuno K, Nakayama E, Noyori O, Marzi A, Ebihara H, Irimura T, Feldmann H, Takada A.
    C-type lectins do not act as functional receptors for filovirus entry into cells
    Biochem Biophys Res Commun. 403(1):144-8, 2010
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393133/

立命館大学 薬学部 免疫微生物学研究室

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