Publications before 2017

以下は2017年度までの業績（天ヶ瀬紀久子）

 

学術論文

• Nahla Hamouda, Tatsushi Sano, Yosuke Oikawa, Tohru Ozaki, Masaki Shimakawa, Kenjiro Matsumoto, Kikuko Amagase, Kazuhide Higuchi, Shinichi Kato: Apoptosis, dysbiosis and expression of inflammatory cytokines are sequential events in the development of 5-fluorouracil-induced intestinal mucositis in mice. Basic Clin. Pharmacol. Toxicol. 121, 159-168 (2017).
• Shinichi Kato, Nahla Hamouda, Yoshitaro Kano, Yosuke Oikawa, Yoshinori Tanaka, Kenjiro Matsumoto, Kikuko Amagase, Masaki Shimakawa: Probiotic Bifidobacterium bifidum G9-1 attenuates 5-fluorouracil-induced intestinal mucositis in mice via suppression of dysbiosis-related secondary inflammatory responses. Clin. Exp. Pharmacol. Physiol. 44, 1017-1025 (2017).
• Takuya Tsukahara, Nahla Hamouda, Daichi Utsumi, Kenjiro Matsumoto, Kikuko Amagase, Shinichi Kato: G protein-coupled receptor 35 contributes to mucosal repair in mice via migration of colonic epithelial cells. Pharmacol. Res. 123, 27-39 (2017).
• Tatsushi Sano, Daichi Utsumi, Kikuko Amagase, Kenjiro Matsumoto, Makoto Tominaga, Kazuhide Higuchi, Tetsu Takeuchi, Shinichi Kato: Lafutidine, a histamine H2 receptor antagonist with mucosal protective properties, attenuates 5-fluorouracil-induced intestinal mucositis in mice through activation of extrinsic primary afferent neurons. J. Physiol. Pharmacol. 68, 79-90 (2017).
• Haruka Yokota, Ayaka Tsuzuki, Yuuki Shimada, Azusa Imai, Daichi Utsumi, Takuya Tsukahara, Misaki Matsumoto, Kikuko Amagase, Kazumi Iwata, Akio Nakamura, Chihiro Yabe-Nishimura, Shinichi Kato: NOX1/NADPH oxidase expressed in colonic macrophages contributes to the pathogenesis of colonic inflammation in trinitrobenzene sulfonic acid-induced murine colitis. J. Pharmacol. Exp. Ther. 360, 192-200 (2017).
• Daichi Utsumi, Kenjiro Matsumoto, Kikuko Amagase, Syunji Horie, Shinichi Kato: 5-HT3 receptors promote colonic inflammation via activation of substance P/neurokinin-1 receptors in dextran sulphate sodium-induced murine colitis. Br. J. Pharmacol. 173, 1835-1849 (2016).
• 天ヶ瀬紀久子, 村上季子, 熊谷みなみ, 西村杏璃, 岡　美里, 河上ひかる, 竹内孝治, 大草貴之: 「スナネズミにおけるヘリコバクターピロリ誘起胃粘膜病変に対する大草胃腸薬の保護作用」 Pharmacol. Ther. 44, 1733-1739 (2016).
• Shinichi Kato, Shusaku Hayashi, Yumeno Kitahara, Koyo Nagasawa, Hitomi Aono, Junichiro Shibata, Daichi Utsumi, Kikuko Amagase, Makoto Kadowaki: Saireito (TJ-114), a Japanese traditional herbal medicine, reduces 5-fluorouracil-induced intestinal mucositis in mice by inhibiting cytokine-mediated apoptosis in intestinal crypt cells. PLoS One 10, e0116213, 1-15 (2015).
• Kikuko Amagase, Nahoko Izumi, Yuka Takahira, Tomoko Wada, Koji Takeuchi: Importance of cyclooxygenase-1/prostacyclin in modulating gastric mucosal integrity under stress conditions. J. Gastroenterol. Hepatol. S4, 3-10 (2014).
• Koji Takeuchi, Shinichi Takayama, Erika Hashimoto, Misaki Itayama, Kikuko Amagase, Chitose Izuhara: Effect of rebamipide on gastric bleeding and ulcerogenic responses induced by aspirin plus clopidogrel under stimulation of acid secretion in rats. J. Gastroenterol. Hepatol. S4, 37-46 (2014).
• Koji Takeuchi, Chitose Izuhara, Shinichi Takayama Takumi Momode, Masahiro Kojo, Daisuke Hara, Kikuko Amagase. Animal models of gastric bleeding induced by dual antiplatelet therapy using aspirin and clopidogrel -Prophylactic effect of antiulcer drugs- Curr. Pharm. Des. 20, 1139-1148 (2014).
• Shusaku Hayashi, Naoto Kurata, Aya Yamaguchi, Kikuko Amagase, Koji Takeuchi: Lubiprostone prevents nonsteroidal anti-inflammatory drug-induced small intestinal damage by suppressing the expression of inflammatory mediators via EP4 receptors. J. Pharmacol. Exp. Ther. 349, 470-479 (2014).
• Hiroshi Satoh, Kikuko Amagase, Koji Takeuchi: Mucosal protective agents prevent exacerbation of NSAID-induced small intestinal lesions caused by antisecretory drugs in rats. J. Pharmacol. Exp. Ther. 348, 227-235, (2014).
• Kenjiro Matsumoto, Takuji Hosoya, Eriko Ishikawa, Kimihito Tashima, Kikuko Amagase, Shinichi Kato, Toshihiko Murayama, Syunji Horie: Distribution of transient receptor potential cation channel subfamily V member 1-expressing nerve fibers in mouse esophagus. Histochem. Cell Biol. 142, 635-644 (2014).
• 天ヶ瀬紀久子, 村上季子, 今里彩乃, 竹本春亮, 田中里穂, 加藤伸一, 竹内孝治:「ロキソプロフェン誘起小腸障害に対するプロバイオティクス製剤の効果」 Pharmacol. Ther. 42, 581-589 (2014).
• Kikuko Amagase, Yuki Kimura, Akimitsu Wada, Tohru Yukishige, Toshiko Murakami, Eiji Nakamura and Koji Takeuchi: Prophylactic effect of monosodium glutamate on NSAID-Induced enteropathy in rats. Curr. Pharm. Des. 20, 2783-2790 (2014).
• Melinda Gyenge, Kikuko Amagase, Shino Kunimi, Rie Matsuoka, Koji Takeuchi: Roles of pro-angiogenic and anti-angiogenic factors as well as matrix metalloproteinases in healing of NSAID-induced small intestinal ulcers in rats. Life Sci. 93, 441-447 (2013).
• Shusaku Hayashi, Naoto Kurata, Emi Kitahirachi, Yushi Nishimura, Kikuko Amagase, Tetsuo Yano, Koji Takeuchi: Cinacalcet, a calcimimetic, prevents nonsteroidal antiinflammatory drug-induced small intestinal damage in rats. J. Physiol. Pharmacol. 64, 453-463 (2013).
• Hiroshi Satoh, Kikuko Amagase, Koji Takeuchi: The role of food for the formation and prevention of gastrointestinal lesions induced by aspirin in cats. Dig. Dis. Sci. 58, 2840-2849 (2013).
• Hiroshi Satoh, Kikuko Amagase, Satomi Ebara, Yasutada Akiba, Koji Takeuchi: Dual control of duodenal mucosal protection by cyclooxygenase (COX)-1 and COX-2 in cats. J. Pharmacol. Exp. Ther., 344: 189-195 (2013).
• Motonobu Murakami, Mayu Fukuzawa, M Yamamoto, K Hamaya, Y Tamura, A Sugiyama, Rei Takahashi, Toshiko Murakami, Kikuko Amagase, Koji Takeuchi: Effects of Helicobacter pylori infection on gastric parietal cells and E-cadherin in Mongolian gerbils. Pharmacol. Sci., 121, 305-311 (2013).
• Masashi Yasuda, Naoki Yamanaka, Maho Iimori, Daichi Utsumi, Yumeno Kitahara, Kikuko Amagase, Shinichi Kato, Koji Takeuchi: Serotonin 5-HT3 receptor antagonists ameliorate 5-fluorouracil-induced intestinal mucositis by suppression of apoptosis in mice intestinal crypt cells. Br. Pharmacol., 168: 1388-1400 (2013).
• Kikuko Amagase, Yushi Yoshida, Daisuke Hara, Toshiko Murakami, Koji Takeuchi: Prophylactic effect of egualen Na, a stable azulene derivative, on gastrointestinal damage induced by ischemia/reperfusion, double antiplatelet therapy and loxoprofen in rats. Physiol. Pharmacol., 64, 65-75 (2013).
• Kikuko Amagase, Akimu Ochi, Azusa Kojo, Ami Mizunoe, Masaya Taue, Naoya Kinoshita, Eiji Nakamura, Koji Takeuchi: New therapeutic strategy for amino acid medicine: Prophylactic and healing promoting effect of monosodium glutamate against NSAID-induced enteropathy. Pharmacol. Sci., 118, 131-137 (2012).
• Masashi Yasuda, Shinichi Kato, Naoki Yamanaka, Maho Iimori, Daichi Utsumi, Yumeno Kitahara, Kazumi Iwata, Kuniharu Matsuno, Kikuko Amagase, Chihiro Yabe-Nishimura, Koji Takeuchi: Potential role of the NADPH oxidase NOX1 in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice. J. Physiol., 302, G1133-G1142 (2012).
• 天ヶ瀬紀久子、高田　彩、本田康裕、中矢有華、幸重　徹、浅川啓紀、岩瀬博明、家高敏彰、竹内孝治: スナネズミにおけるHelicobacter pylori誘起胃粘膜病変に対する御岳百草丸の保護作用. 薬理と治療, 40, 413-420 (2012).
• Shinichi Kato, Narumi Matsuda, Kenjiro Matsumoto, Mai Wada, Naoki Onimaru, Masashi Yasuda, Kikuko Amagase, Syunji Horie, Koji Takeuchi: Dual role of serotonin in the pathogenesis of indomethacin- induced small intestinal ulceration: Pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors. Res., 66, 226-234 (2012).
• Hiroshi Satoh, Kikuko Amagase, Koji Takeuchi: Exacerbation of nonsteroidal anti-inflammatory drug-induced small intestinal lesions by antisecretory drugs in rats: The role of intestinal motility. Pharmacol. Exp. Ther., 343, 270-277 (2012).
• Ryoji Kawahara, Masashi Yasuda, Hiroshi Hashimura, Kikuko Amagase, Shinichi Kato, Koji Takeuchi: Activation of α7 nicotinic acetylcholine receptors ameliorates indomethacin-induced small intestinal ulceration in mice. J. Pharmacol., 650, 411-417 (2011).
• Hironori Takasuka, Shusaku Hayashi, Masafumi Koyama, Masashi Yasuda, Eitaro Aihara, Kikuko Amagase, Koji Takeuchi: Carbon monoxide involved in modulating HCO3- secretion in rat duodenum. J. Pharmacol. Exp. Ther., 337, 293-300 (2011).
• Masashi Yasuda, Ryoji Kawahara, Hiroshi Hashimura, Naoki Yamanaka, Maho Iimori, Kikuko Amagase, Shinichi Kato, Koji Takeuchi: Dopamine D2-receptor antagonists ameliorate indomethacin-induced small intestinal ulceration in mice by activating a7 nicotinic acetylcholine receptors. J. Pharmacol. Sci., 116, 274-282 (2011).
• Koji Takeuchi, Akiko Tanaka, Kazuo Nukui, Azusa Kojo, Melinda Gyenge, Kikuko Amagase: Aggravation by paroxetine, a selective serotonin reuptake inhibitor, of antral lesions generated by nonsteroidal anti-inflammatory drugs in rats. J. Pharmacol. Exp. Ther., 338, 850-859 (2011).
• Yuuki Kawahara, Yuki Nakase, Yui Isomoto, Narumi Matsuda, Kikuko Amagase, Shinichi Kato, Koji Takeuchi: Role of macrophage colony-stimulating factor (M-CSF)-dependent macrophages in gastric ulcer healing in mice. J. Physiol. Pharmacol., 62, 441-448 (2011).
• Kikuko Amagase, Aya Inaba, Toshihiro Senta, Yuka Ishikawa, Kazuo Nukui, Toshiko Murakami, Koji Takeuchi: Gastric ulcerogenic and healing impairment effects of risedronate, a nitrogen-containing bisphosphonate, in rats: Comparison with alendronate and minodronate. Physiol. Pharmacol., 62, 609-618 (2011).
• Kikuko Amagase, Eiji Nakamura, Takuya Endo, Shusaku Hayashi, Mai Hasumura, Hisayuki Uneyama, Kunio Torii, Koji Takeuchi: New frontiers in gut nutrient sensor research: Prophylactic effect of glutamine against helicobacter pylori-induced gastric diseases in mongolian gerbils. Pharmacol. Sci., 112, 25-32 (2010).
• 岡部　進、中川加奈子、天ヶ瀬紀久子: 胃粘膜防御薬イルソグラジンマレイン酸塩のAspirin誘起ラット小腸損傷に対する予防効果. 薬理と治療, 38, 297-302 (2010).
• Kenichi Nonoyama, Kanako Nakagawa, Kikuko Amagase, Koji Takeuchi, Masahiko Nakamura, Susumu Okabe: New method of inducing intestinal lesions in rats by intraduodenal administration of aspirin. Gastroenterol. Hepatol., 25, S15-S22 (2010).
• Koji Takeuchi, Mayu Tanigami, Kikuko Amagase, Akimu Ochi, Sayaka Okuda, Ryo Hatazawa: Endogenous prostaglandin E2 accelerates healing of indomethacin-induced small intestinal lesions through upregulation of vascular endothelial growth factor expression by activation of EP4 receptors. Gastroenterol. Hepatol., 25, S67-S74 (2010).
• Kikuko Amagase, Akimu Ochi, Tetsuya Sugihara, Shinichi Kato, Koji Takeuchi: Protective effect of lafutidine, a histamine H2 receptor antagonist, against loxoprofen-induced small intestinal lesions in rats. Gastroenterol. Hepatol., 25, S111-S118 (2010).
• Tetsuya Sugihara, Ayako Kobori, Hirotsugu Imaeda, Tomoyuki Tsujikawa, Kikuko Amagase, Koji Takeuchi, Yoshihide Fujiyama, kira Andoh. The increased mucosal mRNA expressions of complement C3 and interleukin-17 in inflammatory bowel disease. Exp. Immunol., 160, 386-393 (2010).
• Yukiko Yoda, Kikuko Amagase, Shinichi Kato, Satoshi Tokioka, Mitsuyuki Murano, Kazuki Kakimoto, Hikaru Nishio, Eiji Umegaki, Koji Takeuchi, Kazuhide Higuchi: Prevention by lansoprazole, a proton pump inhibitor, of indomethacin-induced small intestinal ulceration in rats through induction of heme oxygenase-1.  Physiol. Pharmacol., 61, 287-294 (2010).
• Yoshikazu Kubo, Aiko Kumano, Kohei Kamei, Kikuko Amagase, Naoko Abe, Koji Takeuchi: Urocortin prevents indomethacin-induced small intestinal lesions in rats through activation of CRF2 receptors. Dis. Sci., 55, 1570-1580 (2010).
• Koji Takeuchi, Shinichi Kato, Kikuko Amagase: Prostaglandin EP receptors involved in modulating gastrointestinal mucosal integrity. Pharmacol. Sci., 114, 248-261 (2010).
• Koji Takeuchi, Akiko Tanaka, Shinichi Kato, Kikuko Amagase, Hiroshi Satoh: Roles of COX inhibition in pathogenesis of NSAID-induced small intestinal damage. Chim. Acta., 411, 459-466 (2010).
• Yukiko Murashima, Tohru Kotani, Shusaku Hayashi, Yoshino Komatsu, Akari Nakagiri, Kikuko Amagase, Koji Takeuchi: Impairment by 5-fluorouracil of the healing of gastric lesions in rats: Effect of lafutidine, a histamine H2 receptor antagonist, mediated by capsaicin-sensitive afferent neurons. Dis. Sci., 54, 36-45 (2009).
• Kazuhide Higuchi, Yukiko Yoda, Kikuko Amagase, Shinichi Kato, Satoshi Tokioka, Mitsuyuki Murano, Koji Takeuchi, Eiji Umegaki: Prevention of NSAID-induced small intestinal mucosal injury: Prophylactic potential of lansoprazole. Clin. Biochem. Nutr., 45, 58-63 (2009).
• Shinichi Kato, Ryoji Kawahara, Masashi Yasuda, Kikuko Amagase, Koji Takeuchi: Aggravation of cold-restraint stress-induced gastric lesions in adjuvant arthritic rats: Pathogenic role of inducible and endothelial nitric oxide. Pharmacol. Sci., 111, 244-252 (2009).
• Ludmila Filaretova, Tatiana Bagaeva, Kikuko Amagase, Koji Tekeuchi: Contribution of glucocorticoids to protective influence of preconditioning mild stress against stress-induced gastric erosions. N.Y. Acad. Sci., 1148, 209-212 (2008).
• 天ヶ瀬紀久子、依田有紀子、越智暁夢、竹内孝治: 特集 消化管粘膜防御製剤の新たな可能性を求めて. インドメタシン誘起小腸傷害に対するテプレノンの有用性. 消化器の臨床, 11, 31-36 (2008).
• Takashi Ohno, Youichiro Hattori, Rie Komine, Takako Ae, Sumito Mizuguchi, Katsuharu Arai, Takeo Saeki, Tatsunori Suzuki, Kanako Hosono, Izumi Hayashi, Yoshio Oh-hashi, Yukiko Kurihara, Hiroki Kurihara, Kikuko Amagase, Susumu Okabe, Katsunori Saigenji, Masataka Majima: Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis. Gastroenterology, 134, 215-225 (2008).
• Kohei Kamei, Yoshikazu Kubo, Naho Kato, Ryo Hatazawa, Kikuko Amagase, Koji Takeuchi: Prophylactic effect of irsogladine maleate against indomethacin-induced small intestinal lesions in rats.  Dis. Sci., 53, 2657-2666 (2008).
• Tohru Kotani, Yukiko Murashima, Atsushi Kobata, Kikuko Amagase, Koji Takeuchi: Pathogenic importance of pepsin in ischemia/reperfusion-induced gastric injury. Life Science, 80, 1984-1992 (2007).
• 小谷　透、林　周作、村嶋祐己子、天ヶ瀬紀久子、加藤伸一、竹内孝治: 抗癌剤5-フルオロウラシル (5-FU) による急性胃粘膜損傷の治癒遅延：ヒスタミンH2受容体拮抗薬ラフチジンの知覚神経を介した改善作用. 薬理と治療, 35, 459-468 (2007).
• 中村英志、林　周作、遠藤拓也、天ヶ瀬紀久子、岡部　進、竹内孝治: Helicobacter pylori誘起胃粘膜病変に対するグルタミンおよびマーズレンの保護作用. 薬理と治療, 35, 479-488 (2007).
• 粟飯原永太郎、伊勢文孝、大橋由美、天ヶ瀬紀久子、竹内孝治: アレンドロネート誘起胃幽門洞損傷に対するマレイン酸イルソグラジンの効果. 薬理と治療, 35, 587-599 (2007).
• Kikuko Amagase, Shusaku Hayashi, Kaoru Nishikawa, Eitaro Aihara, Koji Takeuchi: Impairment of gastric ulcer healing by alendronate, a nitrogen-containing bisphosphonate, in rats. Dig. Dis. Sci., 52, 1879-1889 (2007).
• Koji Takeuchi, Akiko Tanaka, Shinichi Kato, Eitaro Aihara, Kikuko Amagase: Effect of (S)-4-(1-(5-chloro-2-(4-fluorophenyoxy) benzamido) ethyl) benzoic acid (CJ-42794), a selective antagonist of prostaglandin E receptor subtype 4, on ulcerogenic and healing responses in rat gastrointestinal mucosa. Pharmacol. Exp. Ther., 322, 903-912 (2007).
• Eitaro Aihara, Shusaku Hayashi, Kikuko Amagase, Shinichi Kato, Koji Takeuchi: Prophylactic effect of rebamipide against the irritative and healing impairment actions of alendronate in rat stomachs. Inflammopharmacology, 15, 196-202 (2007).
• Kaoru Nishikawa, Kikuko Amagase, Koji Takeuchi: Effect of dopamine on the healing of acetic acid-induced gastric ulcers in rats. Inflammopharmacology, 15, 209-213 (2007).
• Ryo Hatazawa, Akiko Tanaka, Mayu Tanigami, Kikuko Amagase, Shinichi Kato, Yasuko Ashida, Koji Takeuchi: Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcers via EP4 receptors. Am J. Phisiol. Gastrointest. Liver Physiol., 293, G788-G797 (2007).
• Shinichi Kato, Yasuyuki Ito, Hikaru Nishio, Yoko Aoi, Kikuko Amagase, Koji Takeuchi: Increased susceptibility of small intestine to NSAID-provoked ulceration in rats with adjuvant-induced arthritis: involvement of enhanced expression of TLR4. Life Science, 81, 1309-1316 (2007).
• Atsushi Kobata, Tohru Kotani, Yoshino Komatsu, Kikuko Amagase, Shinichi Kato, Koji Takeuchi: Dual action of nitric oxide in the pathogenesis of ischemia/reperfusion-induced mucosal injury in mouse stomach. Digestion, 75, 188-197 (2007).
• Tohru Kotani, Atsushi Kobata, Eiji Nakamura, Kikuko Amagase, Koji Takeuchi: Roles of Cyclooxygenase-2 and prostacyclin/IP receptors in mucosal defense against ischemia/reperfusion injury in mouse stomach. J Pharmacol Exp Ther, 316, 547-555 (2006).
• Natarajan Venkatesan, Kaori Uchino, Kikuko Amagase, Yukako Ito, Nobuyuki Shibata, Kanji Takada. Gastro-intestinal patch system for the delivery of erythropoietin. J Control Release, 111, 19-26 (2006).
• 粟飯原永太郎、林　周作、天ヶ瀬紀久子、加藤伸一、竹内孝治: アレンドロネートによる胃粘膜障害の発生および潰瘍の治癒遅延に対するレバミピドの影響. 薬理と治療, 34, 305-316 (2006).
• Tohru Kotani, Toshio Fujimura, Kikuko Amagase, Susumu Okabe, Koji Takeuchi: A novel gastric lesion model induced in rats by partial gastric vascular ligation. Inflammopharmacology, 13, 261-272 (2005).
• Yukako Ito, Biranchinarayan Tosh, Yusuke Togashi, Kikuko Amagase, Tsunao Kishida, Tsunataro Kishida, Nobuyuki Sugioka, Nobuhito Shibata, Kanji Takada: Absorption of interferon alpha from patches in rats. Journal of Drug Targeting, 13, 383-390 (2005).
• Kikuko Amagase, Susumu Okabe: On the mechanisms underlying histamine induction of gastric mucosal lesions in rats with partial gastric vascular occlusion. J. Pharmacol. Sci., 92, 124-136 (2003).
• Kikuko Amagase, Mika Yokota, Yasuhiro Tsukimi, Susumu Okabe: Characterization of "unhealed gastric ulcers" produced with chronic exposure of acetic acid ulcers to indomethacin in rats. J. Physiol. Pharmacol., 54, 349-360 (2003).
• Kikuko Amagase, Susumu Okabe: Acetic acid ulcers : a new method for producing solitary chronic ulcers in rat stomachs by intraluminal application of acetic acid solution. Inflammopharmacology, 10, 385-389 (2002).
• Yasuhiro Tsukimi, Keiko Kanatani, Kikuko Amagase, Susumu Okabe: Protective effect of roxatidine for taurocholate-induced cell damage in RGM-1 cells: Involvment of a 70 k-Da heat shock protein. Dig. Protec., 3, 9-17 (2002).
• Susumu Okabe, Kenichi Shimosako, Kikuko Amagase: Pharmacological regulation of gastric acid secretion in the apical membrane of parietal cells : A new target for antisecretory drugs. Physiol. Pharmacol., 52, 639-656 (2001).
• Yasuhiro Tsukimi, Hiromi Nakai, Shingo Itoh, Kikuko Amagase, Susumu Okabe: Involvement of heat shock proteins in the healing of acetic acid-induced gastric ulcers in rats. Physiol. Pharmacol., 52, 391-406 (2001).
• Kikuko Amagase, Kyoko Ikeda, Susumu Okabe: Antisecretory and ulcer healing effects of S-0509, a novel CCK-B/gastrin receptor antagonist, in rats. Dis. Sci., 44, 879-888 (1999).
• Kikuko Amagase, Susumu Okabe: A new ulcer model, "unhealed gastric ulcers", induced by chronic treatment with indomethacin in rats with acetic acid ulcers. Physiol. Pharmacol., 50, 169-181 (1999).
• 天ヶ瀬紀久子、池田恭子、岩井ちさと、松本裕子、岡部　進：シメチジンおよびセトラキサート配合薬（DH4701）のラット急性胃損傷の発生および基礎胃酸分泌に対する効果. Res., 20, 189-197 (1999).
• 岡部　進、天ヶ瀬紀久子、南出晃伸、岸本悦子、北田佳奈: 消化酵素ビオジアスターゼ2000およびプロザイム6のラット慢性胃潰瘍の治癒に対する影響. Res., 18, 259-265 (1997).
• Susumu Okabe, Kikuko Amagase, Hiromi Fujita, Kazumi Iwata, Nobuhiro Satake, Shoji Shibata: Vasoinhibitory effect of leminoprazole, a H+, K+-ATPase inhibitor, on rat aortic rings. Pharmacol., 27, 117-121 (1996).
• Kikuko Amagase, Shinichi Kato, Hiroshi Yamamoto, Susumu Okabe: Effects of the novel histamine H2-receptor antagonist (±)-(E)-1-[2-hydroxy-2-(4-hydroxyphenyl)ethyl]-3-[2-[[[5-(methylamino)methyl -2-furyl]methyl]thio]ethyl]-2-(methylsulfonyl) guanidine on gastric secretion and gastroduodenal ulcers in rats. Forsch. Drug Res., 46, 177-184 (1996).
• 岡部　進、天ヶ瀬紀久子、藤本宗一、藤田博巳: メチルメチオニンスルホニウムクロライド（MMSC）のラット胃粘膜細胞に対する保護作用について. Res., 17, 343-349 (1996).

 

総説

• Koji Takeuchi, Kikuko Amagase: Roles of prostaglandin E and EP receptors in mucosal protection and ulcer healing in the gastrointestinal tract. Dig. Disord. 1, 4-12 (2017).
• 天ヶ瀬紀久子、中村英志、加藤伸一、竹内孝治.「グルタミン酸の消化管粘膜保護薬としての可能性」薬学雑誌135, 779-782 (2016).
• Koji Takeuchi, Masanori Takeeda, Kikuko Amagase, Masato Nakashima. "Regulatory mechanism of the gastric hyperemic response following barrier disruption: Roles of cyclooxygenase-1, the prostaglandin E2/EP1 receptor and sensory neurons. Curr. Pharm. Des. 21, 1-10 (2015).
• Michiyo Akagi, Kikuko Amagase, Toshiko Murakami, Koji Takeuchi: Irsogladine: Overview of the mechanisms of mucosal protective and healing-promoting actions in the gastrointestinal tract. Curr. Pharm. Des. 19, 106-114 (2013).
• 竹内孝治、田中晶子、加藤伸一、天ヶ瀬紀久子: NSAID起因性小腸損傷の発生−COX 阻害の病因論的役割−. 日本薬理学雑誌 139, 103-108 (2012).
• 天ヶ瀬紀久子、中村英志、加藤伸一、竹内孝治. 「グルタミン酸による消化管粘膜保護作用」薬学雑誌131, 1711-1719, (2011).
• 竹内孝治、天ヶ瀬紀久子: NSAIDのピットフォール. 特集 薬剤性潰瘍の実態と対応: 低用量アスピリン、NSAIDを中心に. 実験治療, 701, 20-24 (2011).
• Koji Takeuchi, Shinichi Kato, Kikuko Amagase: Gastric ulcerogenic and healing impairment actions of alendronate, a nitrogen-containing bisphosphonate: Prophylactic effects of rebamipide. Curr. Pharmaceutical Design, 17, 1602-1611 (2011).
• 天ヶ瀬紀久子、加藤伸一、竹内孝治: 胃酸および十二指腸アルカリ分泌調節におけるムスカリン受容体サブタイプ4の重要性. 特集 最近注目されている消化管の受容体. I.Research, 19, 17-23 (2011).
• 加藤伸一、天ヶ瀬紀久子、竹内孝治: a7ニコチン性アセチルコリン受容体. 特集 最近注目されている消化管の受容体. I.Research, 19, 49-56 (2011).
• Susumu Okabe, Kikuko Amagase, Koji Takeuchi: Acetic acid ulcer model: State of the arts in 2010. Polish Gastroenterology, 17, 165-168 (2010).
• 竹内孝治、天ヶ瀬紀久子、阿部尚子、湖城　梓: 図説：アスピリン潰瘍の発症機序とその特徴. 日本臨床, 68, 1962-1965 (2010).
• 加藤伸一、天ヶ瀬紀久子、竹内孝治: 非ステロイド性抗炎症薬(NSAID)誘起小腸傷害の病態生理:関節炎発症時における小腸障害の増悪. 日本薬理学雑誌, 133, 203-205 (2009).
• 竹内孝治、天ヶ瀬紀久子、越智暁夢、西尾　光: 特集 “Helicobacter pylori感染と低用量アスピリンによる胃粘膜傷害”. 動物実験におけるアスピリン胃粘膜傷害. Helicobacter Research, 13, 117-122 (2009).
• 竹内孝治、天ヶ瀬紀久子、熊野愛子: 特集 “高齢者とNSAIDs惹起性消化管傷害”. アスピリンによる胃粘膜傷害の発生機序. 老年消化器病, 21, 31-36 (2009).
• 加藤伸一、天ヶ瀬紀久子、竹内孝治: 新消化管の分子生物学 第6回. 消化管カプサイシン感受性知覚神経の分子生物学. I. Research, 17, 361-366 (2009).
• 竹内孝治、谷上真由、天ヶ瀬紀久子: NSAID誘起消化管障害におけるCOX阻害の意義、特集 ”NSAID起因性消化管病変”. GI Research, 15: 455-463 (2007).
• 竹内孝治、小谷　透、粟飯原永太郎、天ヶ瀬紀久子：プロスタグランジンの消化管粘膜保護作用とEP受容体サブタイプ．サイトプロテクション-生体防御機構の解明と最先端医療への道-．峯　徹哉　監修, 癌と化学療法社, 61-70 (2006).
• Susumu Okabe, Kikuko Amagase: An overview of acetic acid ulcer models --the history and state of the art of peptic ulcer research. Pharm. Bull., 28, 1321-1341 (2005).
• 天ヶ瀬紀久子、竹内孝治: 消化性潰瘍治癒のメカニズム−胃潰瘍治癒の質にかかわる因子. 医学のあゆみ, 210, 1707-1711 (2004).
• Takeshi Aihara, Eiji Nakamura, Kikuko Amagase, Kazuyoshi Tomita, Teruaki Fujishita, Kazuharu Furutani, Susumu Okabe: Pharmacological control of gastric acid secretion for the treatment of acid-related peptic disease: past, present, and future. Ther., 98, 109-127 (2003).
• 岡部　進、天ヶ瀬紀久子: 消化性潰瘍の治癒機構および治療薬の開発に対する考案1）酢酸潰瘍モデルの考案と薬効評価を中心にして. 日本薬理学雑誌, 122, 73-92 (2003).

 

著書

• 天ヶ瀬紀久子、竹内孝治: 「消化器系に作用する薬」薬害副作用学. 図解 薬害・副作用学　改訂2版, 川西正祐、小野秀樹、賀川義之編集, pp. 406-413, 南山堂 (2017).
• 竹内孝治、天ヶ瀬紀久子: シンプル薬理学、第12章：消化器作用薬、改訂第4版、野村隆英、石川直久 編集、南江堂、 291-310 (2014) 
• 竹内孝治、天ヶ瀬紀久子: 基礎コース細胞生物学（原著第3版）, 永田恭介監訳. pp. 157-174, 東京化学同人 (2013).
• 竹内孝治、天ヶ瀬紀久子: 消化器系に作用する薬.みてわかる薬学 図解 薬害・副作用学, 川西正祐、小野秀樹、賀川義之編集, pp. 278-285, 南山堂 (2013).
• 竹内孝治、天ヶ瀬紀久子、加藤伸一: 消化器系および炎症関連用語. 薬学用語辞典, 日本薬学会 編集, 東京化学同人 (2012).
• 天ヶ瀬紀久子、竹内孝治: 消化器疾患、胃潰瘍・十二指腸潰瘍. “薬局”増刊号、病気と薬パーフェクトBOOK 2012, 横田千津子、池田宇一、大越教夫 監修・編集, pp. 364-372, pp. 379-381, 南山堂 (2012).
• Susumu Okabe, Kikuko Amagase, and Koji Takeuchi: Acetic acid ulcer model - State of the art in 2012. In: Cell/Tissue Injury and Cytoprotection/Organoprotection in the Gastrointestinal Tract: Mechanisms, Prevention and Treatment, edited by Ludmila Filaretova and Koji Takeuchi, pp. 32-40, Karger (2012).
• Koji Takeuchi and Kikuko Amagase: Evaluation of gastric ulcerogenic and healing impairment effects of bisphosphonates: Adverse gastric reactions of bisphosphonate. In: Current Protocols in Toxicology: Gastrointestinal Toxicology, Chapter 53: Unit 21; 10.1-10.29, John Wiley & Sons, Inc. (2012).
• 竹内孝治、天ヶ瀬紀久子、谷中昭典: 第9章 消化器系に作用する薬物. 最新基礎薬理学 第3版, 竹内孝治、岡　淳一郎 編集, 高木敬次郎、亀山　勉、岡部　進 監修, pp. 257-286, 廣川書店 (2011).
• 天ヶ瀬紀久子、竹内孝治: 消化器疾患、胃潰瘍・十二指腸潰瘍. “薬局”増刊号、病気と薬パーフェクトBOOK 2011, 横田千津子、池田宇一、大越教夫 監修・編集, pp. 408-415, pp. 425-427, 南山堂 (2011).
• 竹内孝治、天ヶ瀬紀久子: 消化器疾患、食道炎・胃炎. 胃潰瘍・十二指腸潰瘍. 病気と薬 パーフェクトBOOK 2010, 横田千津子、池田宇一、大越教夫 監修・編集, pp. 396-398, 407-410, 南山堂 (2010).
• 竹内孝治、天ヶ瀬紀久子: 消化器疾患作用薬、食道炎・胃炎. 胃潰瘍・十二指腸潰瘍. 病気と薬 パーフェクトBOOK 2009, 横田千津子、池田宇一、大越教夫 監修・編集, pp. 315-318, 326-329, 南山堂 (2009).
• 依田有紀子、梅垣英次、竹内利寿、森田英次郎、村野実之、時岡　聡、天ヶ瀬紀久子、加藤伸一、竹内孝治、樋口和秀: Ⅳ. 2.NSAIDs小腸傷害の現状と対策–ランソプラゾールの可能性を含めて–. 炎症免疫応答とプロトンポンプインヒビター, 吉川敏一 監修, pp. 110-116, 診断と治療社 (2009).
• 竹内孝治、天ヶ瀬紀久子: 消化器疾患作用薬、食道炎・胃炎. 胃潰瘍・十二指腸潰瘍. 病気と薬 パーフェクトBOOK 2008, 池田宇一、大越教夫、横田千津子 監修・編集, pp. 314-316, 326-329, 南山堂 (2008).
• Koji Takeuchi, Shinichi Kato, Akiko Tanaka, Kikuko Amagase, and Eiji Nakamura: Prostaglandin EP receptor subtypes and gastrointestinal mucosal protection. “Pathophysiological and Biochemical Analyses of “Life-Style Related or Intractable Diseases” - Target Validation for Drug Therapy - ”, edited by Nishino T. and Takeuchi K., pp. 243-262, Research Signpost (2006).
• Koji Takeuchi, Kazuhiro Fukushima, Kikuko Amagase, Tohru Kotani : Regulatory mechanism of gastric hyperemic response following challenge with mild irritants – Role of prostaglandins and EP receptor subtypes - Mediators in Gastrointestinal Protection and Repair. Edited by Koji Takeuchi and Gyula Mozsik.  Research Signpost, Keraka, India, pp.87-105, (2004).
• Susumu Okabe, Kikuko Amagase: Does hypergastrinemia beneficially affect healing of experimental gastric ulcers? Gastrin in the New Millenium. Edited by J.L.Marchant.  Cure Foundation, USA, pp.197-205, (2004).
• 岡部　進、天ヶ瀬紀久子、毛戸祥博、江畑未紗子、中井宏美、小野敦子、藤下晃章: 実験胃潰瘍モデル−Shay潰瘍からHelicobacter pylori感染潰瘍まで−. 胃粘膜のBioregulation, 荒川哲男, 吉川敏一 編, ライフサイエンス, 東京, pp123-145 (2003).
• Susumu Okabe, Kenichi Shimosako, Kikuko Amagase, and Teruaki Fujishita: Pharmacological control of gastric acid secretions via the apical membrane of parietal cells in dogs.  Mechanism and Consequences of Proton Transport, Edited by Tetsuro Urushidani, John G. Forte, George Sachs. Kluwer Academic Publishers, London, pp. 305-313 (2002).
• Susumu Okabe, Chiharu Nozue, Kikuko Amagase: Mechanism by which omeprazole and leminoprazole enhance healing of acetic acid gastric ulcers in rats : Role of circulating gastrin. Gastroduodenal Mucosal Damage : Problems of Protection and Healing. Edited by R. Cheli, G. Iaquinto, S. Szabo.  Mediserve, Italy, pp.169-182, (1997).